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hypoxanthine$37115$ - translation to English
GROUP OF PROTEINS WITH HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE ACTIVITY
HPRT; HGPRT; Hypoxanthine phosphoribosyltransferase; Hypoxanthine/guanine phosphoribosyl transferase; Hypoxanthine phosphoribosyltransferase 1; HPRT1; Hgprt; Hprt; Hypoxanthine-guanine phosphoribosyl transferase; Hypoxanthine guanine phosphoriberyltransform; Hypoxanthine guanine phosphoribory itransferase; High-performace guanine phophoriboost transferase; Hypoxanthine guanine phosphoribosyl transferase; HPRT1 (gene); EC 2.4.2.8; GPRT; IMP:diphosphate phospho-D-ribosyltransferase
hypoxanthine
n. Hypoxanthin, chemische Verbindung in Pflanzen- und Tiergewebe
Definition
inosine
['?n?(?)si:n]
¦ noun Biochemistry a compound which is formed in the metabolism of purine and is a nucleoside containing ribose.
Origin
Wikipedia
Hypoxanthine-guanine phosphoribosyltransferase
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene.
HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. This reaction transfers the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate (PRPP) to the purine. HGPRT plays a central role in the generation of purine nucleotides through the purine salvage pathway.
